In 2223 A.D., the migration of the human race to the outer space started by the discovery of "Inflation hall" which made super-speed of light transport possible. The Inflation hall connects the Saturn`s satellite Titan to the outer space, and is controlled by ancient ruins "Watcher`s nest".
However, this useful system as transportation to the outer space unexpectedly summons the alien who is called "Ghoul".
A 18-year-old girl Misaki who enlisted in Seraphim which was the army established to prevent the invasion of Ghoul finished training in the solar system, and went to Watcher`s nest which was the next training place, and was the relay station of Inflation hall in the distance of 32 light year from the earth. However, monster Ghoul from the outer space has already approached there. Misaki encounters Ghoul, and becomes Morph:Divergence EVE shouldering the cursed fate as Designer`s Children and keeps fighting. Fear changes a girl to the weapon.
Sci-fi, horror and bishojo anime created by the same director and character designer as Amazing Nurse Nanako, who is famous for enormeous breasts.

Episode 1 starts just before last episode. Episode 2 is a true start. The meaning of Divergence EVE is clarified by the final episode.